Research Scientist

Position: Scientific - Research ScientistLocation: San Diego, CA*OnsiteDuration: 12+ Months (Extendable) This Position is Onsite . Pay Rate: $52.00hr Client: PharmaJob Description: Standard work schedule Research Scientist Location: San Diego, CA. 100% Onsite. **TOP SKILLS: • Ph.D. in cell biology, immunology, molecular biology, oncology or equivalent field • Knowledge and experience in using multi-parameter flow cytometry • Hands-on experience with mammalian cell culture, molecular and cellular technologies (e.g., CRISPRCas9 knock-inout, lentiviral transduction, western blotting, quantitative PCR,) and functional assays (e.g., proliferation, apoptosis, cell cycle) is essential • Experience in utilizing platforms including IncuCyte, JESS, Flow based cell sorter, ELISA, and MSD in the context of oncology-based drug discovery is a plus *RESPONSIBILITIES* • Utilize and develop multiple disease models to design target validation studies and relevant assays in support of SAR, mechanism of action, mechanisms of resistance, biomarker selection, and disease positioning. • Develop and implement cell-based assays to address both tumor intrinsic cellular biology and immune-based mechanisms of action for potential drug candidates • Design and conduct essential mechanistic experiments in cell biology, cellular biochemistry, molecular biology, and assay development • Accurately maintain written reports and present results in an organized and timely manner. • Communicate effectively, foster teamwork, and contribute to collaborative efforts. • Strong commitment to quality and demonstrate adaptability. *QUALIFICATIONS* • Ph.D. in cell biology, immunology, molecular biology, or equivalent field with 0-2 years of post-doc or industry experience, or M.S. degree with 3+ years of experience, or Bachelor's degree with 5+ years of experience in the biopharmaceutical industry developing and optimizing cell-based assays, preferably in Oncology • Strong background and experience in cancer research with training in molecular and cell biology • Extensive experience using multi-parameter flow cytometry in the context of primary immune cell isolation and characterization is required. • Extensive hands-on experience with mammalian cell culture, molecular and cellular technologies (e.g., CRISPRCas9 knock-inout, lentiviral transduction, western blotting, quantitative PCR,) and functional assays (e.g., proliferation, apoptosis, cell cycle) is essential • Experience in utilizing platforms including IncuCyte, JESS, Flow based cell sorter, ELISA, and MSD in the context of oncology-based drug discovery is a plus. • Strong record of high-impact and rigorous science though publication history. • Proficiency in scientific data analysis programs including GraphPad Prism, FlowJo, Microsoft ExcelPowerpoint, is required • Capability to deliver high quality data in an organized and timely manner • Ability to work in a fast-paced dynamic team environment; flexibility to adapt to changes with a positive attitude and independently collaborate across teams, requiring excellent communication skills, both written and verbal, with strong interpersonal skills.

Created: 2024-11-01