Senior Research Associate - Structural Biology
SciPro - redwood city, CA
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Senior Research Associate - Structural Biology (X-Ray Crystallography)Location: Redwood City, CA (mostly lab work, therefore 100% onsite - with flexi hours)Terms: 12mth contract to hireUnder the mentorship of a Scientist I, and joining a team of 5, we are seeking an SRA with a background working on Oncology programs, to support generation of protein crystal structures. From the bench, you will work on protein purification, identification and optimization of crystallization conditions, and routine production and harvesting of co-crystals of protein and small molecules. **We are seeking an individual that is at an SRA level already. Experience, Skills, & Education: MSc. degree in biology, biochemistry, enzymology or related field with 1-2+ yrs industry experience OR BSc. and min. 3-5+years.Experience with protein handling, characterization, and storage (FPLC or HPLC techniques like SEC and affinity chromatography. PAGE, quantitation via Bradford and nanodrop etc.).Experience with protein-protein complexes including antibodiesFabs, molecular glues, PROTACs, etc.BENEFICIAL SKILLSExperience with growing and harvesting protein crystals highly desirable.Prior use of crystallographic software suites (CCP4, Phenix) and visualization software (PyMOL, Chimera).Experience with biophysical characterization such as MS, Thermal Shift Analysis, SPR a plus.Experience with protein-ligand crystallization and refinement.Experience in protein expression including construct design and protein engineering.
Created: 2024-11-01