Senior Scientist, Biology
SiteOne Therapeutics, Inc. - san francisco, CA
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SummarySiteOne Therapeutics is seeking a highly motivated Senior Scientist I with a focus in peripheral neuroscience to join our research biology group. The individual will participate in the design and execution of experiments in biological systems to characterize and validate targettherapeutic mechanism of action, and screen for potency and efficacy of small molecule drug candidates via in vitro and in vivo assays. The successful candidate will use their knowledge, experience, and skills to manage and conduct research activities, analyze preclinical and clinical literatures, develop hypotheses, and contribute to the company's research and development efforts to create high value therapeutics. Key Responsibilities Lead the design and execution of preclinical cell based and biochemical studies as well as in vivo efficacy models. Contribute at the bench, collaborate cross-functionally, involve in scientific, technical discussion and data presentation at research and project teams. Ideal Candidate PhD in neuroscience or related areas with at least 3 years relevant industry work experience. Experience in small molecule drug discovery including molecular biology, cell culture and cell line development, cell-based assay development, patch clamp electrophysiology. Solid foundation and proficient in relevant in-vitro ex-vivo experimental biology techniques such as Western blotting, qPCR, biochemical assays, cell-based signaling and functional assays. Experience in designing and running in-vivo pain models in mice and rats. Proficiency in software for analyzing data, such as Prism, Excel, or other relevant scientific applications is required. Ability to interpret and report results and effectively communicate with broad research and project teams. Capability of evaluating scientific literature to stay current within field of research. Excellent interpersonal skills with the ability to work both independently and cross-functionally to advance drug discovery programs. About SiteOne Therapeutics:SiteOne Therapeutics is a clinical-stage biopharmaceutical company advancing a novel class of highly selective small molecule inhibitors targeting NaV1.7, NaV1.8, and other ion channels to treat peripheral hypersensitivity disorders such as chronic cough, itch, and pain. Since its inception, SiteOne has been dedicated to the development of safe and effective pain therapeutics without the significant addiction potential and side effects of opioids. The company's website can be found at
Created: 2024-10-05