Associate Scientist

R&D Partners is seeking to hire an Associate Scientist II in San Carlos, CAA rapidly growing vaccine company is looking for an Associate Scientist II who will contribute to the research and development of a novel bacterial polysaccharide conjugate vaccine. The candidate will work within the Research Department to perform analytical assays and characterization testing for in-process intermediates and drug substances.Your main responsibilities as an Associate Scientist II:Routine in-house testing, buffer preparation, sample analysis, data reporting, instrument purchase, qualification, maintenance, troubleshooting, lab safety, etc.You will be working with a cross-functional team to streamline core analytical characterization technologies to meet the vaccine pipeline development timeline, some of which include HPLC-SEC, RP-HPLC, SEC-MALS, GCMS or HPAEC-PAD, SDS-PAGE, Western Blot, colorimetric plate-based assays, BCA, Anthrone, PicoGreen, ELISA, MSD, DSF, CE-SDS, and CE-IEF.Independently perform routine in-house assays and buffer preparations to analyze and characterize our in- process intermediates and drug substances, which consist of protein, polysaccharides, and protein- polysaccharide conjugates. Assays include: HPLC-SEC, RP-HPLC, SEC-MALS; GCMS or HPAEC-PAD SDS-PAGE, Western Blot, microplate assays, both colorimetric (BCA, Anthrone, PicoGreen) and enzyme-based assays (ELISA/MSD); DSF, CE-SDS, and CE-IEFResponsible for routine instrument maintenance (HPLC, SEC-MAL, GCMS, HPEAC-PAD) and troubleshooting.Assist in the development of new analytical assays and methods.Troubleshoot various issues during analytical method development and routine sample testing.What we are looking for in an Associate Scientist II:A BS in chemistry, analytical chemistry preferred, and organic / biochemistry considered, with 2+ years of relevant industry experience or an MS with 1+ year experience.Direct experience operating Agilent HPLC using OpenLab/ Chemstation software and/or Waters UPLC and Empower software for data acquisition and analysis.Broad hands-on experience with chemical and biological assays such as colorimetric/ fluorometric microplate assays, HPLC, CE, UV-Vis, ELISA, and LC-MS.Experience with mass spectrometry, GCMS, or HPAEC-PAD is highly desired.Understand basic principles of analytical method development/ validation/ qualification concepts.This position is lab-based and requires onsite presence 5 days a week.Pay Scale:$85,000 - $91,500 annuallyR&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies.R&D Partners is an equal-opportunity employer.

Created: 2025-01-15