Director of Immunology

Synnovation Therapeutics is a precision medicine company developing small molecule therapies optimized to achieve best-in-class pharmacology against highly validated disease targets. Synnovation's pipeline is built around discovering compounds with greater selectivity and optimized pharmaceutical properties that have the potential to address liabilities in existing standards of care and meaningfully improve patient outcomes.We are looking for a highly motivated and creative individual with a strong background in Immunology and drug discovery to join our team. The candidate will play a critical role in the discovery and development of novel therapeutics for inflammatory or autoimmune diseases by working with discovery, translational and clinical teams to select, characterize and advance candidates into clinical development.The title will be commensurate with the successful candidate's experience. The position will be based in Synnovation's headquarters in Wilmington, DE.Key Responsibilities:Provide subject area expertise and leadership for autoimmune/inflammation drug discovery projectsDevise and execute immunology experiments to support clinical candidate selectionWork with internal team and CROs to characterize in vitro and in vivo pharmacologyCollaborate with translational scientists to characterize pathway biomarkersPresent clearly and succinctly in a variety of team settingsProvide mentorship to junior scientistsMinimum Requirements:Ph.D. in immunology, Immuno-oncology or related field with 8+ years of industry experience and a proven track record of productivity (as demonstrated by patent applications and publications)Experience leading cross-functional teams and programs from discovery to the clinicDeep understanding of biological pathways and therapeutic rationale for autoimmune and inflammatory drug targetsAbility to design, perform and interpret in vitro immunology assays to support lead optimization and candidate selectionKnowledge of in vivo disease models of inflammation and autoimmunity and ability to design pharmacology experiments to demonstrate the impact of small molecules on immune cell responses and disease modificationPrior experience directing work with contract research organizations or managing collaboratorsExcellent communication skills to develop and communicate complex data sets in a clear and concise manner to different audiencesPreferred Qualifications:Experience with pharmacology of small molecule drugs including characterization of drug mechanism of action on immune cell functions in vitro and in vivoUnderstanding of and experience with drug discovery and development processes for immunology programs and ability to collaborate across preclinical, translational and clinical teamsEmbraces opportunities and challenges of rapid-paced start-up environment.Demonstrated experience in people managementTranslational medicine expertise spanning discovery to the clinicStrong organizational and time-management skills including the ability to manage several projects simultaneouslyIndependent, creative, highly motivated team playerAll applicants should be legally entitled to work for any employer in the U.S.Equal Opportunity EmployerSynnovation Therapeutics, Inc is an equal opportunity employer committed to diversity and inclusion in the workplace. We encourage applications from individuals of all backgrounds and experiences.Note to Employment Agencies: Please do not forward any agency resumes. The company will not responsible for any fees related to resumes that are unsolicited.

Created: 2025-01-14