Research Associate/Senior Research Associate, ...

Colossal is looking for a talented biologist with a strong interest in applying synthetic biology to create innovative genetic constructs for the modification of mammalian traits. In this high-impact role, you will work closely with a cross-functional team to drive novel applications in the modification of phenotypes across a variety of species. You will have the opportunity to significantly influence the direction of the project and make an impact across Colossal.This position is based on-site in Dallas, TX. Relocation assistance is available. Duties and Responsibilities: Perform molecular cloning and troubleshooting of plasmids and gene constructs.Genotype clones of interest and resolve any issues in the process.Work to improve throughput in clonal generation by integrating automation into molecular and cellular workflows.Collaborate with stem cell biologists to optimize gene editing and novel gene integration delivery methods in mammalian models.Analyze and interpret data, making informed decisions to steer the project forward.Contribute to patent generation, helping to protect innovative work and discoveries.Attend lab meetings, prepare reports, and present findings to ensure team alignment and progress on milestones.Demonstrate excellent organizational skills and maintain accurate, detailed lab records.Required Skills and Abilities:Strong hands-on research experience with molecular cloning, plasmid troubleshooting, and gene construct development.Experience with gene-editing tooling (CRISPR Cas9 HDR).Proficient in molecular biology techniques, including DNARNA extraction, protein isolation, and qPCR.Experience with genotyping design and troubleshooting assays in cellular and mouse models.Excellent organizational skills, ability to handle multiple projects concurrently, and meet deadlines.Strong written and oral communication skills, along with creative problem-solving abilities.Adaptability in a fast-paced, dynamic work environment.Preferred Skills and Abilities:Experience tagging proteins with fluorophores and expressing fluorophores from ectopic & native enhancers.Experience with high-throughput automation platforms.Familiarity with plate reader instruments and Shimadzu UV-Vis Software.Experience working with bacterial expression systems and their application to mammalian models.Education and Experience:BABSMAMS in biological sciences, bioengineering, molecular biology, genetics, or any science related field.What Colossal Offers You:Medical, dental, and vision coverageUnlimited PTO and company holidays so you can rest and recharge Flexible spending accounts (FSA)Company matched 401k retirement planPaid parental leave up to 12 weeksEducation reimbursement An opportunity to help us return the Earth to a healthier stateThe team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That's why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices. Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we're doing something big. Something Colossal.Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive. EEO is the Law Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house. Colossal is proud to be named a Best Place to Work by BuiltIn for 3 years in a row across multiple categories in 2023, 2024, and 2025:#1 on the 50 Best Startups to Work For in Dallas in 2023!100 Best Midsize Places to Work in Dallas in 2024 & 2025100 Best Places to Work in Dallas, TX (All Size Employers) in 2024 & 2025100 Best Midsize Places to Work in Boston in 2024 & 2025 Built In 2025 Award ListsGreat Place to Work Certification PageMost Loved Workplace Certification Page - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.Newsweek's Most Loved Workplaces 2024 Award List - Excited to be amongst the winners of Newsweek's 2024 Most Loved Workplaces!

Created: 2025-03-04