Associate Researcher I - Structural Biology Research - ...

Job DescriptionAre you passionate about unraveling the mysteries of proteins and their role in diseases such as Alzheimer's and cancer? The Wang Laboratory at the Icahn School of Mount Sinai is seeking a motivated researcher to dive into groundbreaking structural biology research. The Associate Researcher will gain hands on experience with cutting edge techniques such as cryo-EM and X-ray crystallography in a collaborative environment. This is an incredible opportunity for recent graduates to enhance their skills and contribute to higher impact projects.The Associate Researcher will work closely with a multidisciplinary team to express, purify, and analyze proteins of interest, contributing to structural studies that aim to understand the molecular mechanisms underlying disease. The role will involve conducting molecular biology and biochemistry experiments, supporting protein structure determination, and assisting in the preparation of experimental results for publication and presentation.ResponsibilitiesConduct protein expressions in bacterial, insect and mammalian systemsPurify proteins using techniques such as affinity chromatography, size exclusion chromatography, and other biochemical methodsAssist in preparing samples for structural studies using cryo-electron microscopy (cryo-EM) and X-Ray crystallographyPerform routine molecular biology tasks, including cloning, PCR and mutagenesisAssist with structural and functional assays, including bio-physical characterization (e.g. fluorescence based assays, electrophoresis)Contribute to laboratory maintenance, inventory and organization of reagents and samplesParticipate in weekly laboratory meetings and contribute to research discussionsCollaborate with lab members on data analysis, and documentation of experimental protocolsQualificationsBachelors or Masters degree in science in biochemistry, molecular biology, biophysics or a related field1 - 2 years of researchlaboratory experienceExperience in molecular biology techniques such as PCR, cloning, and protein expressionFamiliarity with cell culture, baculovirus systems or tissue culture workExperience with protein purification techniques (e.g. affinity chromatography, gel filtration)Strong organizational skills and attention to detailGood communications skills and ability to work as part of a teamWillingness to learn new techniques and solve complex problemsAbout UsStrength Through Diversity The Mount Sinai Health System believes that diversity, equity, and inclusion are key drivers for excellence. We share a common devotion to delivering exceptional patient care. When you join us, you become a part of Mount Sinai's unrivaled record of achievement, education, and advancement as we revolutionize medicine together. We invite you to participate actively as a part of the Mount Sinai Health System team by: Using a lens of equity in all aspects of patient care delivery, education, and research to promote policies and practices to allow opportunities for all to thrive and reach their potential. Serving as a role model confronting racist, sexist, or other inappropriate actions by speaking up, challenging exclusionary organizational practices, and standing side-by-side in support of colleagues who experience discrimination. Inspiring and fostering an environment of anti-racist behaviors among and between departments and co-workers. At Mount Sinai, our leaders strive to learn, empower others, and embrace change to further advance equity and improve the well-being of staff, patients, and the organization. We expect our leaders to embrace anti-racism, create a collaborative and respectful environment, and constructively disrupt the status quo to improve the system and enhance care for our patients. We work hard to create an inclusive, welcoming and nurturing work environment where all feel they are valued, belong and are able to advance professionally. Explore more about this opportunity and how you can help us write a new chapter in our history! "About the Mount Sinai Health System: Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 43,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time - discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients' medical and emotional needs at the center of all treatment. The Health System includes approximately 7,400 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics and top 20 in CardiologyHeart Surgery, DiabetesEndocrinology, GastroenterologyGI Surgery, NeurologyNeurosurgery, Orthopedics, PulmonologyLung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report's "Best Children's Hospitals" ranks Mount Sinai Kravis Children's Hospital among the country's best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 14 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek's "The World's Best Smart Hospitals" ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally. The Mount Sinai Health System is an equal opportunity employer. We comply with applicable Federal civil rights laws and does not discriminate, exclude, or treat people differently on the basis of race, color, national origin, age, religion, disability, sex, sexual orientation, gender identity, or gender expression. We are passionately committed to addressing racism and its effects on our faculty, staff, students, trainees, patients, visitors, and the communities we serve. Our goal is for Mount Sinai to become an anti-racist health care and learning institution that intentionally addresses structural racism." EOE MinoritiesWomenDisabledVeterans

Created: 2025-02-25